Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM28577'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM28577 (1-sulfonylindazole, 6f | 3-(diethylamino)-N-[1-(na...) Show SMILES CCN(CC)CCC(=O)Nc1ccc2cnn(c2c1)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C24H26N4O3S/c1-3-27(4-2)15-14-24(29)26-20-13-12-19-17-25-28(22(19)16-20)32(30,31)23-11-7-9-18-8-5-6-10-21(18)23/h5-13,16-17H,3-4,14-15H2,1-2H3,(H,26,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.10	-49.0	n/a	n/a	n/a	n/a	n/a	7.4	22
Wyeth Research					Assay Description Competition experiments were performed in the presence radioligand with membrane protein (obtained from cells expressing the receptor) and test compo...				Bioorg Med Chem Lett 19: 2413-5 (2009) Article DOI: 10.1016/j.bmcl.2009.03.071 BindingDB Entry DOI: 10.7270/Q28K77CF
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