Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50313124'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313124 (1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2O2S/c1-24-14-13-18(15-24)25-16-23(20-10-4-5-11-21(20)25)28(26,27)22-12-6-8-17-7-2-3-9-19(17)22/h2-12,16,18H,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 2 hrs				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50313124 (1-(1-methylpyrrolidin-3-yl)-3-(naphthalen-1-ylsulf...) Show SMILES CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2ccccc12 Show InChI InChI=1S/C23H22N2O2S/c1-24-14-13-18(15-24)25-16-23(20-10-4-5-11-21(20)25)28(26,27)22-12-6-8-17-7-2-3-9-19(17)22/h2-12,16,18H,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity at human 5-HT6 receptor expressed in human HeLa cells assessed as inhibition of 5HT-induced intracellular cAMP level after 10 min...				Bioorg Med Chem Lett 20: 1657-60 (2010) Article DOI: 10.1016/j.bmcl.2010.01.073 BindingDB Entry DOI: 10.7270/Q2ZC830C
					More data for this Ligand-Target Pair