BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50361053'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length human 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (RAT)	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length rat 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (RAT)	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length rat 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length human 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length human 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361053 (CHEMBL1935601) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.80	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5-HT6 receptor expressed human astrocytoma cells assessed as inhibition of 5-HT-induced cAMP accumulation af...				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
Cephalon, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair