Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat)) | BDBM50130261 (6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.99 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University Curated by ChEMBL | Assay Description Binding affinity for rat serotonin 5-HT7 receptor expressed in Sf9 cells using [3H]-5-HT radioligand | Bioorg Med Chem Lett 15: 747-50 (2005) Article DOI: 10.1016/j.bmcl.2004.11.013 BindingDB Entry DOI: 10.7270/Q2WD4027 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50130261 (6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Virginia Commonwealth University Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor | J Med Chem 46: 2795-812 (2003) Article DOI: 10.1021/jm030030n BindingDB Entry DOI: 10.7270/Q2M0465F | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50130261 (6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hungarian Academy of Sciences Curated by ChEMBL | Assay Description Displacement of [3H]5-CT from recombinant human 5-HT7 receptor expressed in COS-7 cell membranes after 30 mins by liquid scintillation counting metho... | Bioorg Med Chem Lett 28: 2418-2421 (2018) Article DOI: 10.1016/j.bmcl.2018.06.019 BindingDB Entry DOI: 10.7270/Q26W9DPS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50130261 (6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Compound was tested for its binding affinity in 5-hydroxytryptamine 7 receptor (using human cloned receptors in HEK 293 and [3H]5-CT as a radioligand... | Bioorg Med Chem Lett 12: 3341-4 (2002) BindingDB Entry DOI: 10.7270/Q2FT8P7C | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50130261 (6-(2-{2-[4-(4-Chloro-phenoxy)-piperidin-1-yl]-ethy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Displacement of [3H]-5-CT from human 5-HT7b receptor expressed in HEK293 cells after 1 hr | Eur J Med Chem 56: 348-360 (2012) Article DOI: 10.1016/j.ejmech.2012.07.043 BindingDB Entry DOI: 10.7270/Q28P61N6 | |||||||||||
More data for this Ligand-Target Pair |