BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-lipoxygenase' and Ligand = 'BDBM50052466'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-lipoxygenase


(Bos taurus)		BDBM50052466
PNG
(3-(4,5-Dihydroxy-10-oxo-9,10-dihydro-anthracen-9-y...)
Show SMILES OC(=O)CCSC1c2cccc(O)c2C(=O)c2c(O)cccc12
Show InChI InChI=1S/C17H14O5S/c18-11-5-1-3-9-14(11)16(22)15-10(4-2-6-12(15)19)17(9)23-8-7-13(20)21/h1-6,17-19H,7-8H2,(H,20,21)
PDB
MMDB

Reactome pathway

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 2.00E+3n/an/an/an/an/an/a



Universität Regensburg

Curated by ChEMBL


Assay Description
Tested for inhibition of 5-lipoxygenase as inhibition of 5-HETE and LTB4 biosynthesis in bovine PMNL

J Med Chem 39: 3132-8 (1996)


Article DOI: 10.1021/jm960259l
BindingDB Entry DOI: 10.7270/Q2MK6BZ1
More data for this
Ligand-Target Pair