Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM196900'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM196900 (US9212192, 63) Show SMILES COc1cc(ccc1Nc1nc(Cc2ccccc2F)n2cnnc2c1C(N)=O)C1CCNCC1 Show InChI InChI=1S/C25H26FN7O2/c1-35-20-12-16(15-8-10-28-11-9-15)6-7-19(20)30-24-22(23(27)34)25-32-29-14-33(25)21(31-24)13-17-4-2-3-5-18(17)26/h2-7,12,14-15,28,30H,8-11,13H2,1H3,(H2,27,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	8	-46.2	n/a	n/a	n/a	n/a	n/a	7.4	25
AbbVie Inc. US Patent					Assay Description ALK kinase assays were conducted with the indicated final concentrations unless otherwise specified. In 384 well black plates (Axygen), 8 ul of compo...				US Patent US9212192 (2015) BindingDB Entry DOI: 10.7270/Q2D79971
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