BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DHX29' and Ligand = 'BDBM65493'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-dependent RNA helicase DHX29 (Homo sapiens (Human))	BDBM65493 (eIF4A3 inhibitor, 2) Show SMILES Show InChI	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminal full length FLAG-His-tagged DHX29 RNA dependent ATPase activity expressed in baculovirus infected Sf9 inse...				ACS Med Chem Lett 8: 1077-1082 (2017) Article DOI: 10.1021/acsmedchemlett.7b00283 BindingDB Entry DOI: 10.7270/Q2QJ7KT3
Takeda Pharmaceutical Company Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-dependent RNA helicase DHX29 (Homo sapiens (Human))	BDBM65493 (eIF4A3 inhibitor, 2) Show SMILES Show InChI	MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
BC Cancer Agency					Assay Description Inhibitory activity was assessed under the following conditions: 350 uM ATP/1.5 ug mL−1 RNA indicated by black; 35 uM ATP/1.5 ug mL−1 RNA...				ACS Chem Biol 12: 1760-1768 (2017) Article DOI: 10.1021/acschembio.7b00041 BindingDB Entry DOI: 10.7270/Q2T151TG
BC Cancer Agency					More data for this Ligand-Target Pair