Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acetylcholine receptor subunit alpha/Neuronal acetylcholine receptor subunit beta-4 (Homo sapiens (Human)) | BDBM50014210 (1-(1H-Indol-3-yl)-2-propanamine | 1-(1H-indol-3-yl...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
UCL School of Pharmacy Curated by ChEMBL | Assay Description Displacement of [3H]Epibatidine from human recombinant alpha2beta4 nACh receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation counti... | Bioorg Med Chem Lett 23: 3411-5 (2013) Article DOI: 10.1016/j.bmcl.2013.03.066 BindingDB Entry DOI: 10.7270/Q2474C7G | |||||||||||
More data for this Ligand-Target Pair |