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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid ceramidase' and Ligand = 'BDBM319789'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acid ceramidase


(Rattus norvegicus (Rat))		BDBM319789
PNG
(US10174015, Compound 2)
Show SMILES O=C(CCCCCc1ccccc1)N1CCOC1=O
Show InChI InChI=1S/C15H19NO3/c17-14(16-11-12-19-15(16)18)10-6-2-5-9-13-7-3-1-4-8-13/h1,3-4,7-8H,2,5-6,9-12H2
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 270n/an/an/an/an/an/a



Chinese Academy of Sciences

Curated by ChEMBL


Assay Description
Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis

Eur J Med Chem 139: 214-221 (2017)


Article DOI: 10.1016/j.ejmech.2017.08.004
BindingDB Entry DOI: 10.7270/Q2FR007C
More data for this
Ligand-Target Pair