Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid ceramidase' and Ligand = 'BDBM319818'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid ceramidase (Rattus norvegicus (Rat))	BDBM319818 (US10174015, Compound 31) Show SMILES Oc1ccc(CCCCCC(=O)N2CCOC2=O)cc1 Show InChI InChI=1S/C15H19NO4/c17-13-8-6-12(7-9-13)4-2-1-3-5-14(18)16-10-11-20-15(16)19/h6-9,17H,1-5,10-11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of rat acid ceramidase expressed in HEK293 cells using N-lauroylceramide as substrate after 30 mins by LC-MS analysis				Eur J Med Chem 139: 214-221 (2017) Article DOI: 10.1016/j.ejmech.2017.08.004 BindingDB Entry DOI: 10.7270/Q2FR007C
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