BindingDB PrimarySearch

Found 5 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50005944'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbits				J Med Chem 35: 1609-17 (1992) BindingDB Entry DOI: 10.7270/Q2G44QXN
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Institute for Bio-Medical Research Curated by ChEMBL					Assay Description Inhibitory activity against Acyl coenzyme A:cholesterol acyltransferase 1 obtained from rabbit intestine microsomes				J Med Chem 39: 1262-70 (1996) Article DOI: 10.1021/jm950828+ BindingDB Entry DOI: 10.7270/Q24T6HGW
Institute for Bio-Medical Research Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	152	n/a	n/a	n/a	n/a	n/a	n/a
Azwell Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibitory activity against ACAT from Caco-2 microsome in human				Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ
Azwell Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	191	n/a	n/a	n/a	n/a	n/a	n/a
Azwell Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibitory activity against ACAT from rabbit liver				Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ
Azwell Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005944 (2,2-Dimethyl-dodecanoic acid (2,4,6-trimethoxy-phe...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	1.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
Azwell Inc. Curated by ChEMBL					Assay Description Compound was tested for inhibitory activity against ACAT from rabbit adrenal gland				Bioorg Med Chem Lett 9: 2039-42 (1999) BindingDB Entry DOI: 10.7270/Q2FF3RJJ
Azwell Inc. Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)