Found 3 hits Enz. Inhib. hit(s) with Target = 'Adenosine receptor A3' and Ligand = 'BDBM50427598' Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Adenosine receptor A3
(Homo sapiens (Human)) | BDBM50427598
(CHEMBL2322924)Show SMILES COc1ccc(cc1)C(=O)Nc1nc(C)nc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C20H17N5O2/c1-13-21-17-12-25(15-6-4-3-5-7-15)24-18(17)19(22-13)23-20(26)14-8-10-16(27-2)11-9-14/h3-12H,1-2H3,(H,21,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Firenze
Curated by ChEMBL
| Assay Description
Displacement of [125I]AB-MECA from human A3 adenosine receptor expressed in CHO cells after 60 mins by scintillation counting analysis |
J Med Chem 56: 2256-69 (2013)
Article DOI: 10.1021/jm400068e
BindingDB Entry DOI: 10.7270/Q29K4CKZ |
More data for this
Ligand-Target Pair | |
Adenosine receptor A3
(Homo sapiens (Human)) | BDBM50427598
(CHEMBL2322924)Show SMILES COc1ccc(cc1)C(=O)Nc1nc(C)nc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C20H17N5O2/c1-13-21-17-12-25(15-6-4-3-5-7-15)24-18(17)19(22-13)23-20(26)14-8-10-16(27-2)11-9-14/h3-12H,1-2H3,(H,21,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113907
BindingDB Entry DOI: 10.7270/Q20K2DJC |
More data for this
Ligand-Target Pair | |
Adenosine receptor A3
(Homo sapiens (Human)) | BDBM50427598
(CHEMBL2322924)Show SMILES COc1ccc(cc1)C(=O)Nc1nc(C)nc2cn(nc12)-c1ccccc1 Show InChI InChI=1S/C20H17N5O2/c1-13-21-17-12-25(15-6-4-3-5-7-15)24-18(17)19(22-13)23-20(26)14-8-10-16(27-2)11-9-14/h3-12H,1-2H3,(H,21,22,23,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2021.113907
BindingDB Entry DOI: 10.7270/Q20K2DJC |
More data for this
Ligand-Target Pair | |
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