Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate cyclase type 10 (Homo sapiens (Human)) | BDBM50577233 (CHEMBL4874288) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 225 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi... | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Adenylate cyclase type 10 (Homo sapiens (Human)) | BDBM50577233 (CHEMBL4874288) | PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | 392 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |