Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibition of recombinant human adenylate cyclase 5 expressed in HEK293 cells | Bioorg Med Chem Lett 12: 3085-8 (2002) BindingDB Entry DOI: 10.7270/Q2XW4J5B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity against recombinant human adenylate cyclase 5 expressed in HEK293 cells. | J Med Chem 46: 2177-86 (2003) Article DOI: 10.1021/jm0205604 BindingDB Entry DOI: 10.7270/Q2M32V44 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Adenylate cyclase type 5 (Homo sapiens (Human)) | BDBM50119832 (4-(6-Amino-purin-9-yl)-N-hydroxy-butyramide | CHEM...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 7.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Millennium Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory concentration of the compound against type V Adenyl Cyclase enzyme | Bioorg Med Chem Lett 12: 3089-92 (2002) BindingDB Entry DOI: 10.7270/Q2T43SFX | |||||||||||
More data for this Ligand-Target Pair |