Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Aldo-keto reductase family 1 member B1 (Homo sapiens (Human)) | BDBM50016653 (CHEMBL19187 | N-Benzyl-4-chloro-2-(2,5-dioxo-imida...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human placental aldose reductase (HPAR) activity with glyceraldehyde as substrate | J Med Chem 32: 1208-13 (1989) BindingDB Entry DOI: 10.7270/Q24B309G | |||||||||||
More data for this Ligand-Target Pair |