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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alkaline phosphatase, tissue-nonspecific isozyme' and Ligand = 'BDBM222183'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alkaline phosphatase, tissue-nonspecific isozyme


(Bos taurus (Cattle))		BDBM222183
PNG
(6-(Dimethylamino)-3-(4'-thiomethylphenyl)-2,3-...)
Show SMILES CSc1ccc(cc1)C1NS(=O)(=O)c2cccc3c(ccc1c23)N(C)C
Show InChI InChI=1S/C20H20N2O2S2/c1-22(2)17-12-11-16-19-15(17)5-4-6-18(19)26(23,24)21-20(16)13-7-9-14(25-3)10-8-13/h4-12,20-21H,1-3H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.63E+3n/an/an/an/a9.837



University of Karachi



Assay Description
Alkaline phosphatase (b-TNAP, c-IAP purchased from Calzyme Laboratories, Inc. USA) inhibition assay of different cyclic sulfonamides was performed us...

Bioorg Chem 71: 10-18 (2017)


Article DOI: 10.1016/j.bioorg.2017.01.008
BindingDB Entry DOI: 10.7270/Q26Q1W36
More data for this
Ligand-Target Pair