Found 4 hits Enz. Inhib. hit(s) with Target = 'Alpha-2C adrenergic receptor' and Ligand = 'BDBM81979' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Alpha-2C adrenergic receptor
(RAT) | BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5| Show InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
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DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| 5.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 241: 1092-8 (1987)
BindingDB Entry DOI: 10.7270/Q2F18X7B |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5| Show InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
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DrugBank PC cid PC sid UniChem
Patents
Similars
| PubMed
| 36.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of California
Curated by PDSP Ki Database
| |
J Pharmacol Exp Ther 241: 1092-8 (1987)
BindingDB Entry DOI: 10.7270/Q2F18X7B |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(Homo sapiens (Human)) | BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5| Show InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14) | PDB
UniProtKB/SwissProt
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DrugBank PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 447 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Roche Bioscience
Curated by PDSP Ki Database
| |
Biochem Pharmacol 55: 1035-43 (1998)
Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01 |
More data for this Ligand-Target Pair | |
Alpha-2C adrenergic receptor
(RAT) | BDBM81979
(CAS_5051-62-7 | CAS_65636 | Fluprofylline | Guanab...)Show SMILES [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1c(Cl)cccc1Cl |w:5.5| Show InChI InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| Purchase
DrugBank PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
The Oregon Health Sciences University
Curated by PDSP Ki Database
| |
Proc Natl Acad Sci U S A 83: 8784-8 (1986)
Article DOI: 10.1073/pnas.83.22.8784 BindingDB Entry DOI: 10.7270/Q2V122XD |
More data for this Ligand-Target Pair | |