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Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-mannosidase' and Ligand = 'BDBM50525014'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Alpha-mannosidase


(Canavalia ensiformis)		BDBM50525014
PNG
(CHEMBL4475419)
Show SMILES [H][C@]12COC(=O)N1[C@H](NCCCCCCn1cc(CCC)nn1)[C@@H](O)[C@@H](O)[C@@H]2O |r,@:6|
Show InChI InChI=1S/C18H31N5O5/c1-2-7-12-10-22(21-20-12)9-6-4-3-5-8-19-17-16(26)15(25)14(24)13-11-28-18(27)23(13)17/h10,13-17,19,24-26H,2-9,11H2,1H3/t13-,14-,15+,16+,17+/m1/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
 500n/an/an/an/an/an/an/an/a



University of Sevilla

Curated by ChEMBL


Assay Description
Inhibition of jack bean Lysosomal alpha-mannosidase assessed as residual hydrolytic activity after 10 to 30 mins by spectrophotometric analysis

J Med Chem 62: 5832-5843 (2019)


Article DOI: 10.1021/acs.jmedchem.9b00153
BindingDB Entry DOI: 10.7270/Q22R3W4H
More data for this
Ligand-Target Pair