Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM155392'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Rattus norvegicus (Rat))	BDBM155392 (US9006283, 2) Show SMILES CCOC(=O)c1c(NC(=O)C(=O)N\N=C\c2cccc(OC)c2O)sc2CC(C)CCc12 Show InChI InChI=1S/C22H25N3O6S/c1-4-31-22(29)17-14-9-8-12(2)10-16(14)32-21(17)24-19(27)20(28)25-23-11-13-6-5-7-15(30-3)18(13)26/h5-7,11-12,26H,4,8-10H2,1-3H3,(H,24,27)(H,25,28)/b23-11+	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	8.0	37
Acumen Pharmaceuticals, Inc. US Patent					Assay Description In this assay, assembly of Abeta 1-42 oligomer formation is monitored by FRET using N-terminal conjugates of fluorescein-Abeta 1-42 as both the donor...				US Patent US9006283 (2015) BindingDB Entry DOI: 10.7270/Q24T6H3Z
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