Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50122785'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122785 (4-(6-bromoH-imidazo[1,2-a]pyridin-2-yl)-N,N-dimeth...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(Br)ccc2n1 Show InChI InChI=1S/C15H14BrN3/c1-18(2)13-6-3-11(4-7-13)14-10-19-9-12(16)5-8-15(19)17-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Mental Health Curated by ChEMBL					Assay Description Binding affinity to human beta amyloid plaque in alzheimer's disease patient brain				J Med Chem 50: 4746-58 (2007) Article DOI: 10.1021/jm0702231 BindingDB Entry DOI: 10.7270/Q2WQ06JK
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122785 (4-(6-bromoH-imidazo[1,2-a]pyridin-2-yl)-N,N-dimeth...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(Br)ccc2n1 Show InChI InChI=1S/C15H14BrN3/c1-18(2)13-6-3-11(4-7-13)14-10-19-9-12(16)5-8-15(19)17-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair