Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50173648'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50173648 (2-(4-Bromo-benzyl)-3-{4-[(E)-2-(4-dimethylamino-ph...) Show SMILES CN(C)c1ccc(\C=C\c2ccc(OCC(CO)Cc3ccc(Br)cc3)cc2)cc1 Show InChI InChI=1S/C26H28BrNO2/c1-28(2)25-13-7-20(8-14-25)3-4-21-9-15-26(16-10-21)30-19-23(18-29)17-22-5-11-24(27)12-6-22/h3-16,23,29H,17-19H2,1-2H3/b4-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates				J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR
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