Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Amyloid-beta precursor protein' and Ligand = 'BDBM50173650'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50173650 ((4-{(E)-2-[4-(2,2-Dimethyl-[1,3]dioxan-5-ylmethoxy...) Show SMILES CN(C)c1ccc(\C=C\c2ccc(OCC3COC(C)(C)OC3)cc2)cc1 Show InChI InChI=1S/C23H29NO3/c1-23(2)26-16-20(17-27-23)15-25-22-13-9-19(10-14-22)6-5-18-7-11-21(12-8-18)24(3)4/h5-14,20H,15-17H2,1-4H3/b6-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant for I-125-IMPY binding to amyloid plaques in Alzheimers disease brain homogenates				J Med Chem 48: 5980-8 (2005) Article DOI: 10.1021/jm050166g BindingDB Entry DOI: 10.7270/Q2TB17PR
					More data for this Ligand-Target Pair