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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiopoietin-1 receptor' and Ligand = 'BDBM50379194'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Angiopoietin-1 receptor


(Homo sapiens (Human))		BDBM50379194
PNG
(CHEMBL2010873)
Show SMILES CCc1cnc(Nc2ccc3n(CC(C)C)c4c5CCc6nn(C)cc6-c5c5C(=O)NCc5c4c3c2)nc1
Show InChI InChI=1S/C30H31N7O/c1-5-17-11-32-30(33-12-17)34-18-6-9-24-20(10-18)26-21-13-31-29(38)27(21)25-19(28(26)37(24)14-16(2)3)7-8-23-22(25)15-36(4)35-23/h6,9-12,15-16H,5,7-8,13-14H2,1-4H3,(H,31,38)(H,32,33,34)
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Similars
Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Cephalon, Inc.

Curated by ChEMBL


Assay Description
Inhibition of human recombinant Tie2 expressed in baculovirus expression system using GST-PLCgamma as substrate after 1 hr by time-resolved fluoresce...

J Med Chem 55: 903-13 (2012)


Article DOI: 10.1021/jm201449n
BindingDB Entry DOI: 10.7270/Q2ZS2XHW
More data for this
Ligand-Target Pair