Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Ataxin-1' and Ligand = 'BDBM475941'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ataxin-1 (Homo sapiens (Human))	BDBM475941 (US10865195, Compound 6) Show SMILES C[C@@H]1CN(Cc2coc(CF)n2)CCN1C(=O)\C=C\c1ccc(cc1Cn1nnc(C)n1)C(F)(F)F |r| Show InChI InChI=1S/C23H25F4N7O2/c1-15-11-32(13-20-14-36-21(10-24)28-20)7-8-33(15)22(35)6-4-17-3-5-19(23(25,26)27)9-18(17)12-34-30-16(2)29-31-34/h3-6,9,14-15H,7-8,10-13H2,1-2H3/b6-4+/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description ATX activity was determined by measurement of released choline in reactions containing ATX (10 nM), choline oxidase (0.1 U/ml), HRP (100 U/ml), ample...				US Patent US10865195 (2020) BindingDB Entry DOI: 10.7270/Q2BV7KQF
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