Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 1' and Ligand = 'BDBM50452457'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor 1 (Homo sapiens (Human))	BDBM50452457 (CHEMBL4213559) Show SMILES CC(C)[C@H](CO)NC(=O)N[C@H]1CC[C@H](CC1)Nc1nc(N[C@H](C)CO)nc2ccc(cc12)-c1cccc(F)c1 |r,wU:13.16,10.9,21.22,wD:3.2,(21.75,-9.39,;20.42,-10.15,;19.1,-9.37,;20.41,-11.68,;21.73,-12.46,;23.06,-11.7,;19.07,-12.44,;17.75,-11.67,;17.76,-10.15,;16.42,-12.43,;15.09,-11.65,;13.75,-12.42,;12.42,-11.64,;12.43,-10.1,;13.77,-9.34,;15.09,-10.11,;11.1,-9.32,;11.11,-7.78,;12.45,-7.02,;12.45,-5.48,;13.79,-4.72,;15.11,-5.48,;15.1,-7.02,;16.44,-4.72,;17.76,-5.49,;11.12,-4.7,;9.79,-5.46,;8.46,-4.69,;7.11,-5.45,;7.11,-6.99,;8.44,-7.77,;9.78,-7,;5.77,-7.76,;5.76,-9.3,;4.43,-10.06,;3.1,-9.28,;3.11,-7.74,;1.78,-6.97,;4.44,-6.98,)| Show InChI InChI=1S/C29H39FN6O3/c1-17(2)26(16-38)35-29(39)33-23-10-8-22(9-11-23)32-27-24-14-20(19-5-4-6-21(30)13-19)7-12-25(24)34-28(36-27)31-18(3)15-37/h4-7,12-14,17-18,22-23,26,37-38H,8-11,15-16H2,1-3H3,(H2,33,35,39)(H2,31,32,34,36)/t18-,22-,23+,26+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at human NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 30 mins by radioimmunoassay				Bioorg Med Chem 25: 6680-6694 (2017) Article DOI: 10.1016/j.bmc.2017.11.006 BindingDB Entry DOI: 10.7270/Q2ZW1PG6
					More data for this Ligand-Target Pair
Atrial natriuretic peptide receptor 1 (Rattus norvegicus)	BDBM50452457 (CHEMBL4213559) Show SMILES CC(C)[C@H](CO)NC(=O)N[C@H]1CC[C@H](CC1)Nc1nc(N[C@H](C)CO)nc2ccc(cc12)-c1cccc(F)c1 |r,wU:13.16,10.9,21.22,wD:3.2,(21.75,-9.39,;20.42,-10.15,;19.1,-9.37,;20.41,-11.68,;21.73,-12.46,;23.06,-11.7,;19.07,-12.44,;17.75,-11.67,;17.76,-10.15,;16.42,-12.43,;15.09,-11.65,;13.75,-12.42,;12.42,-11.64,;12.43,-10.1,;13.77,-9.34,;15.09,-10.11,;11.1,-9.32,;11.11,-7.78,;12.45,-7.02,;12.45,-5.48,;13.79,-4.72,;15.11,-5.48,;15.1,-7.02,;16.44,-4.72,;17.76,-5.49,;11.12,-4.7,;9.79,-5.46,;8.46,-4.69,;7.11,-5.45,;7.11,-6.99,;8.44,-7.77,;9.78,-7,;5.77,-7.76,;5.76,-9.3,;4.43,-10.06,;3.1,-9.28,;3.11,-7.74,;1.78,-6.97,;4.44,-6.98,)| Show InChI InChI=1S/C29H39FN6O3/c1-17(2)26(16-38)35-29(39)33-23-10-8-22(9-11-23)32-27-24-14-20(19-5-4-6-21(30)13-19)7-12-25(24)34-28(36-27)31-18(3)15-37/h4-7,12-14,17-18,22-23,26,37-38H,8-11,15-16H2,1-3H3,(H2,33,35,39)(H2,31,32,34,36)/t18-,22-,23+,26+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	65	n/a	n/a	n/a	n/a
Asubio Pharma Co., Ltd Curated by ChEMBL					Assay Description Agonist activity at rat NPR-A expressed in CHO cells assessed as increase in cGMP accumulation after 15 mins by fluorescent assay				Bioorg Med Chem 25: 6680-6694 (2017) Article DOI: 10.1016/j.bmc.2017.11.006 BindingDB Entry DOI: 10.7270/Q2ZW1PG6
					More data for this Ligand-Target Pair