Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50319573'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50319573 (CHEMBL1084453 | N1-(4-(2-(4-(1H-benzo[d]imidazol-2...) Show SMILES CN(C)CC(C)(C)CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nc3ccccc3[nH]2)c2ccccc12 Show InChI InChI=1S/C33H34N8O/c1-33(2,21-41(3)4)20-36-31-35-19-17-26(37-31)24-12-9-18-34-30(24)42-29-16-15-25(22-10-5-6-11-23(22)29)38-32-39-27-13-7-8-14-28(27)40-32/h5-19H,20-21H2,1-4H3,(H,35,36,37)(H2,38,39,40)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.66E+3	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora A				J Med Chem 53: 4502-10 (2010) Article DOI: 10.1021/jm100301x BindingDB Entry DOI: 10.7270/Q2T43T83
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