Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM92832'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM92832 (Bisanilinopyrimidine, 9e) Show SMILES CC(=O)Nc1cccc(Nc2nccc(Nc3ccccc3Cl)n2)c1 Show InChI InChI=1S/C18H16ClN5O/c1-12(25)21-13-5-4-6-14(11-13)22-18-20-10-9-17(24-18)23-16-8-3-2-7-15(16)19/h2-11H,1H3,(H,21,25)(H2,20,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	71.2	n/a	n/a	n/a	n/a	n/a	n/a
Moffitt Cancer Center					Assay Description In vitro enzyme activity assay using Aurora Kinase A.				J Med Chem 55: 7392-416 (2012) Article DOI: 10.1021/jm300334d BindingDB Entry DOI: 10.7270/Q2V986NH
					More data for this Ligand-Target Pair				3D Structure (docked)