Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM155567'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM155567 (US10092556, Example 11 | US9012475, 11 | US9346787...) Show SMILES COc1ccc(CC2(CCN(CC2)C(=O)c2cccc(Cl)c2F)C(O)=O)nc1Nc1cc(C)[nH]n1 Show InChI InChI=1S/C24H25ClFN5O4/c1-14-12-19(30-29-14)28-21-18(35-2)7-6-15(27-21)13-24(23(33)34)8-10-31(11-9-24)22(32)16-4-3-5-17(25)20(16)26/h3-7,12H,8-11,13H2,1-2H3,(H,33,34)(H2,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	930	n/a	n/a	n/a	n/a	7.4	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description The method for measuring the in-vitro inhibitory activity of a test compound against Aurora B kinase activity was substantially the same as in the ca...				US Patent US9012475 (2015) BindingDB Entry DOI: 10.7270/Q2MW2FWZ
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155567 (US10092556, Example 11 | US9012475, 11 | US9346787...) Show SMILES COc1ccc(CC2(CCN(CC2)C(=O)c2cccc(Cl)c2F)C(O)=O)nc1Nc1cc(C)[nH]n1 Show InChI InChI=1S/C24H25ClFN5O4/c1-14-12-19(30-29-14)28-21-18(35-2)7-6-15(27-21)13-24(23(33)34)8-10-31(11-9-24)22(32)16-4-3-5-17(25)20(16)26/h3-7,12H,8-11,13H2,1-2H3,(H,33,34)(H2,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	930	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US10092556 (2018) BindingDB Entry DOI: 10.7270/Q2ZG6V8B
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM155567 (US10092556, Example 11 | US9012475, 11 | US9346787...) Show SMILES COc1ccc(CC2(CCN(CC2)C(=O)c2cccc(Cl)c2F)C(O)=O)nc1Nc1cc(C)[nH]n1 Show InChI InChI=1S/C24H25ClFN5O4/c1-14-12-19(30-29-14)28-21-18(35-2)7-6-15(27-21)13-24(23(33)34)8-10-31(11-9-24)22(32)16-4-3-5-17(25)20(16)26/h3-7,12H,8-11,13H2,1-2H3,(H,33,34)(H2,27,28,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	930	n/a	n/a	n/a	n/a	7.4	n/a
TAIHO PHARMACEUTICAL CO., LTD. US Patent					Assay Description The in vitro method for measuring the inhibitory activity of the test compound on the aurora B kinase activity was performed in a similar manner as t...				US Patent US9346787 (2016) BindingDB Entry DOI: 10.7270/Q28K77Z2
					More data for this Ligand-Target Pair