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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50292244'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase B


(Homo sapiens (Human))		BDBM50292244
PNG
(CHEMBL4175359)
Show SMILES Cc1cc(Nc2cc(nc(Nc3ccc(F)c(Cl)c3)n2)N2CCOCC2)n[nH]1
Show InChI InChI=1S/C18H19ClFN7O/c1-11-8-16(26-25-11)22-15-10-17(27-4-6-28-7-5-27)24-18(23-15)21-12-2-3-14(20)13(19)9-12/h2-3,8-10H,4-7H2,1H3,(H3,21,22,23,24,25,26)
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n/an/a 35n/an/an/an/an/an/a



Sun Yat-sen University

Curated by ChEMBL


Assay Description
Inhibition of AURKB (unknown origin) using FAM-labeled peptide substrate preincubated for 10 mins followed by substrate addition measured after 60 mi...

Eur J Med Chem 145: 805-812 (2018)


Article DOI: 10.1016/j.ejmech.2017.12.082
BindingDB Entry DOI: 10.7270/Q2RX9FMM
More data for this
Ligand-Target Pair