Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase B' and Ligand = 'BDBM50326208'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase B (Homo sapiens (Human))	BDBM50326208 (4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimid...) Show SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nnc(-c3ccc(F)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C30H22FN7O/c1-32-30-34-18-16-26(36-30)25-7-4-17-33-29(25)39-22-14-12-21(13-15-22)35-28-24-6-3-2-5-23(24)27(37-38-28)19-8-10-20(31)11-9-19/h2-18H,1H3,(H,35,38)(H,32,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of Aurora B by HTRF assay				J Med Chem 53: 6368-77 (2010) Article DOI: 10.1021/jm100394y BindingDB Entry DOI: 10.7270/Q2C829H0
					More data for this Ligand-Target Pair
Aurora kinase B (Homo sapiens (Human))	BDBM50326208 (4-(4-Fluorophenyl)-N-(4-(3-(2-(methylamino)pyrimid...) Show SMILES CNc1nccc(n1)-c1cccnc1Oc1ccc(Nc2nnc(-c3ccc(F)cc3)c3ccccc23)cc1 Show InChI InChI=1S/C30H22FN7O/c1-32-30-34-18-16-26(36-30)25-7-4-17-33-29(25)39-22-14-12-21(13-15-22)35-28-24-6-3-2-5-23(24)27(37-38-28)19-8-10-20(31)11-9-19/h2-18H,1H3,(H,35,38)(H,32,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	24	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL					Assay Description Inhibition of aurora B in human HeLa cells assessed as increase of >= 4N DNA level after 24 hrs by Hoechst staining				J Med Chem 53: 6368-77 (2010) Article DOI: 10.1021/jm100394y BindingDB Entry DOI: 10.7270/Q2C829H0
					More data for this Ligand-Target Pair