BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'Bcl-2-like protein 1' and Ligand = 'BDBM31378'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM31378 (CHEMBL284686 \| terephthalamide scaffold, 26) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85E+3	-32.7	n/a	n/a	n/a	n/a	n/a	7.4	25
Yale University					Assay Description Fluorescence polarization experiments were conducted on a Photon Technology International instrument using a 0.3 cm path length cuvette. Spectra were...				J Am Chem Soc 127: 5463-8 (2005) Article DOI: 10.1021/ja0446404 BindingDB Entry DOI: 10.7270/Q29Z937V
Yale University					More data for this Ligand-Target Pair
Bcl-2-like protein 1 (Homo sapiens (Human))	BDBM31378 (CHEMBL284686 \| terephthalamide scaffold, 26) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.85E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Yale University Curated by ChEMBL					Assay Description Binding affinity for Bcl-xL was assessed by a fluorescence polarizationassay using a fluorescently labeled 16-mer Bak-peptide				Bioorg Med Chem Lett 14: 1375-9 (2004) Article DOI: 10.1016/j.bmcl.2003.09.096 BindingDB Entry DOI: 10.7270/Q2D799V3
Yale University Curated by ChEMBL					More data for this Ligand-Target Pair