Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50560174 (GSK789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 6.31E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to full length BRD3 BD2 in human HuT78 cell lysates incubated for 45 mins by liquid chromatography-mass spectrometry based chemoprot... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00614 BindingDB Entry DOI: 10.7270/Q27D2ZVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50560174 (GSK789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to full length BRD3 BD1 in human HuT78 cell lysates incubated for 45 mins by liquid chromatography-mass spectrometry based chemoprot... | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00614 BindingDB Entry DOI: 10.7270/Q27D2ZVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50560174 (GSK789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length BRD3 bromodomain 2 (G306 to P416 residues) expressed in bacterial expression system by BROMOscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00614 BindingDB Entry DOI: 10.7270/Q27D2ZVG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Bromodomain-containing protein 3 (Homo sapiens (Human)) | BDBM50560174 (GSK789) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid PDB UniChem | Article PubMed | n/a | n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human partial length BRD3 bromodomain 1 (P24 to E144 residues) expressed in bacterial expression system by BROMOscan assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c00614 BindingDB Entry DOI: 10.7270/Q27D2ZVG | |||||||||||
More data for this Ligand-Target Pair |