Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assay | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 116 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Displacement of H3K14Ac from BAZ2B (unknown origin) preincubated for 30 mins with non-biotinylated peptide followed by addition of biotinylated pepti... | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 311 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assay | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB PubMed | n/a | n/a | 468 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Oxford Curated by ChEMBL | Assay Description Inhibition of BAZ2A (unknown origin) after 30 mins by AlphaScreen assay | Sci Adv 2: (2016) BindingDB Entry DOI: 10.7270/Q24J0JPZ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Bromodomain-containing protein 4 (Homo sapiens (Human)) | BDBM50504160 (CHEMBL3133807 | US11773085, Compound B25) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem | PDB Article PubMed | n/a | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a |
Moffitt Cancer Center Curated by ChEMBL | Assay Description Binding affinity to recombinant human BRD4 BD1 expressed in Escherichia coli BL21 DE3 assessed as dissociation constant by isothermal titration calor... | J Med Chem 63: 3227-3237 (2020) Article DOI: 10.1021/acs.jmedchem.9b01980 BindingDB Entry DOI: 10.7270/Q26T0R19 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |