Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Bromodomain-containing protein 4 [342-460]/[42-168]' and Ligand = 'BDBM111129'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 [342-460]/[42-168] (Homo sapiens (Human))	BDBM111129 (US9695179, 124) Show SMILES Clc1ccc2c(-c3ccccc3)c(Sc3nc4ccccc4s3)c(=O)[nH]c2c1 Show InChI InChI=1S/C22H13ClN2OS2/c23-14-10-11-15-17(12-14)24-21(26)20(19(15)13-6-2-1-3-7-13)28-22-25-16-8-4-5-9-18(16)27-22/h1-12H,(H,24,26)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	US Patent	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	25
ConverGene LLC US Patent					Assay Description The interactions between test compounds and BRD4 protein containing both bromodomain 1 and bromodomain 2 were measured with human BRD4 protein with N...				US Patent US9695179 (2017) BindingDB Entry DOI: 10.7270/Q21G0JF6
					More data for this Ligand-Target Pair