BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = 'C5a anaphylatoxin chemotactic receptor 1' and Ligand = 'BDBM50251425'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50251425 (2-(2-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]C5a from human recombinant C5a receptor in U937 cells				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair
C5a anaphylatoxin chemotactic receptor 1 (Homo sapiens (Human))	BDBM50251425 (2-(2-(2-(2,6-diethylphenyl)-4-methoxy-5,6,7,8-tetr...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human recombinant C5a receptor in U937 cells assessed as inhibition of C5a-induced calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 18: 3852-5 (2008) Article DOI: 10.1016/j.bmcl.2008.06.059 BindingDB Entry DOI: 10.7270/Q2765F4X
					More data for this Ligand-Target Pair