Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein/Histone acetyltransferase p300' and Ligand = 'BDBM50200432'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50200432 (CHEMBL3917803 | US9763922, Example 222) Show SMILES COCCNC(=O)c1cccc(Nc2nn(CC3CC3)c3CCN(Cc23)C(C)=O)c1 Show InChI InChI=1S/C22H29N5O3/c1-15(28)26-10-8-20-19(14-26)21(25-27(20)13-16-6-7-16)24-18-5-3-4-17(12-18)22(29)23-9-11-30-2/h3-5,12,16H,6-11,13-14H2,1-2H3,(H,23,29)(H,24,25)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Genentech Curated by ChEMBL					Assay Description Displacement of biotinylated ligand from recombinant His-tagged CBP/EP300 (unknown origin) measured after 10 mins by TR-FRET assay				J Med Chem 59: 10549-10563 (2016) Article DOI: 10.1021/acs.jmedchem.6b01022 BindingDB Entry DOI: 10.7270/Q27083DF
					More data for this Ligand-Target Pair