Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'CREB-binding protein/Histone acetyltransferase p300' and Ligand = 'BDBM50286469'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
CREB-binding protein/Histone acetyltransferase p300 (Homo sapiens (Human))	BDBM50286469 (CHEMBL4173894) Show SMILES CNC(=O)Nc1ccc2c(CCC22NC(=O)N(CC(=O)N(Cc3ccccc3)[C@@H](C)C3CC3)C2=O)c1 |r| Show InChI InChI=1S/C27H31N5O4/c1-17(19-8-9-19)31(15-18-6-4-3-5-7-18)23(33)16-32-24(34)27(30-26(32)36)13-12-20-14-21(10-11-22(20)27)29-25(35)28-2/h3-7,10-11,14,17,19H,8-9,12-13,15-16H2,1-2H3,(H,30,36)(H2,28,29,35)/t17-,27?/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie, Inc. Curated by ChEMBL					Assay Description Inhibition of p300/CBP (unknown origin) using biotinylated synthetic Histone H4 Peptide as substrate pretreated for 30 mins followed by substrate add...				ACS Med Chem Lett 9: 28-33 (2018) Article DOI: 10.1021/acsmedchemlett.7b00395 BindingDB Entry DOI: 10.7270/Q2HQ42FP
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