Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Calcium/calmodulin-dependent protein kinase type II subunit delta' and Ligand = 'BDBM292658'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292658 ((S)-N-(2-(diethylamino)propyl)-2-(3-oxopiperazin-1...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CCNC(=O)C1 |r| Show InChI InChI=1S/C27H32N8O2S/c1-4-33(5-2)18(3)15-29-27(37)19-13-22(31-24(14-19)34-11-9-28-25(36)17-34)20-16-30-35-10-8-21(32-26(20)35)23-7-6-12-38-23/h6-8,10,12-14,16,18H,4-5,9,11,15,17H2,1-3H3,(H,28,36)(H,29,37)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description The biochemical activity of recombinant CaMKIIδ was measured by monitoring the phosphorylation of a target peptide using Homogenous Time Resolve...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair
Calcium/calmodulin-dependent protein kinase type II subunit delta (Homo sapiens (Human))	BDBM292658 ((S)-N-(2-(diethylamino)propyl)-2-(3-oxopiperazin-1...) Show SMILES CCN(CC)[C@@H](C)CNC(=O)c1cc(nc(c1)-c1cnn2ccc(nc12)-c1cccs1)N1CCNC(=O)C1 |r| Show InChI InChI=1S/C27H32N8O2S/c1-4-33(5-2)18(3)15-29-27(37)19-13-22(31-24(14-19)34-11-9-28-25(36)17-34)20-16-30-35-10-8-21(32-26(20)35)23-7-6-12-38-23/h6-8,10,12-14,16,18H,4-5,9,11,15,17H2,1-3H3,(H,28,36)(H,29,37)/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	96	n/a	n/a	n/a	n/a
Gilead Sciences, Inc. US Patent					Assay Description CaMKII activity in neonatal rat ventricular myocytes (NRVM) was measured by monitoring the phosphorylation level of phospholamban using high-content ...				US Patent US10100058 (2018) BindingDB Entry DOI: 10.7270/Q2V98B4F
					More data for this Ligand-Target Pair