Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Calcium release-activated calcium channel protein 1' and Ligand = 'BDBM141402'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Calcium release-activated calcium channel protein 1 (Homo sapiens (Human))	BDBM141402 (US10668051, Compound Example 28 | US8921364, 28) Show SMILES Cc1nnsc1C(=O)Nc1ccc(c(F)c1)-n1nc(cc1C1CC1)C1CC1 Show InChI InChI=1S/C19H18FN5OS/c1-10-18(27-24-22-10)19(26)21-13-6-7-16(14(20)8-13)25-17(12-4-5-12)9-15(23-25)11-2-3-11/h6-9,11-12H,2-5H2,1H3,(H,21,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60.3	n/a	n/a	n/a	n/a	n/a	n/a
RHIZEN PHARMACEUTICALS SA US Patent					Assay Description Inhibition of CRAC channels was determined following thapsigargin (Sigma, Cat #T9033) induced endoplasmic calcium release in Jurkat cells, (see Yasur...				US Patent US10668051 (2020) BindingDB Entry DOI: 10.7270/Q2V40Z7G
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