Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carbonic anhydrase 4 (Bos taurus (bovine)) | BDBM50108563 (Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]t...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | PubMed | 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Namur Curated by ChEMBL | Assay Description Inhibitory effect on bovine Carbonic anhydrase IV | J Med Chem 45: 312-20 (2002) BindingDB Entry DOI: 10.7270/Q2ZP46TZ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carbonic anhydrase 4 (Homo sapiens (Human)) | BDBM50108563 (Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]t...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid UniChem Similars | Article PubMed | 349 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Florida Curated by ChEMBL | Assay Description Inhibition of human recombinant carbonic anhydrase 4 after 15 mins by stopped-flow CO2 hydration assay | Bioorg Med Chem Lett 20: 4376-81 (2010) Article DOI: 10.1016/j.bmcl.2010.06.082 BindingDB Entry DOI: 10.7270/Q2C24XCB | |||||||||||
More data for this Ligand-Target Pair |