Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Carboxylic ester hydrolase' and Ligand = 'BDBM173568'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carboxylic ester hydrolase (Equus caballus (Horse))	BDBM173568 (1-(2-Oxo-2H-chromene-3-carbonyl)-3-(2-chlorophenyl...) Show SMILES Clc1ccccc1NC(=S)NC(=O)c1cc2ccccc2oc1=O Show InChI InChI=1S/C17H11ClN2O3S/c18-12-6-2-3-7-13(12)19-17(24)20-15(21)11-9-10-5-1-4-8-14(10)23-16(11)22/h1-9H,(H2,19,20,21,24)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Quaid-I-Azam University					Assay Description Newly synthesized coumarin thioureas were tested against electric eel AChE and horse serum BChE. The cholinesterase inhibitory activity was measured ...				Bioorg Chem 63: 58-63 (2015) Article DOI: 10.1016/j.bioorg.2015.09.009 BindingDB Entry DOI: 10.7270/Q2W957Z4
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