Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Carboxypeptidase B2 (Homo sapiens (Human)) | BDBM50575780 (CHEMBL4878039) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | 0.75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometry | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02072 BindingDB Entry DOI: 10.7270/Q2SB49JM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxypeptidase B2 (Homo sapiens (Human)) | BDBM50575780 (CHEMBL4878039) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human activated TAFI incubated for 45 mins using hippuryl-arginine as substrate by spectrophotometry | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02072 BindingDB Entry DOI: 10.7270/Q2SB49JM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Carboxypeptidase B2 (Rattus norvegicus) | BDBM50575780 (CHEMBL4878039) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | n/a | 389 | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of TAFI in Sprague-Dawley rat blood TAFI incubated for 2 mins using hippuryl-arginine as substrate by thromboelastometry analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c02072 BindingDB Entry DOI: 10.7270/Q2SB49JM | |||||||||||
More data for this Ligand-Target Pair |