Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Casein kinase I isoform delta' and Ligand = 'BDBM302451'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase I isoform delta (Homo sapiens (Human))	BDBM302451 (2-(3-Fluorophenyl)-N5- (2-(4-fluorophenyl) propan-...) Show SMILES CC(C)(NC(=O)N1CCn2nc(c(C(N)=O)c2C1)-c1cccc(F)c1)c1ccc(F)cc1 Show InChI InChI=1S/C23H23F2N5O2/c1-23(2,15-6-8-16(24)9-7-15)27-22(32)29-10-11-30-18(13-29)19(21(26)31)20(28-30)14-4-3-5-17(25)12-14/h3-9,12H,10-11,13H2,1-2H3,(H2,26,31)(H,27,32)	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The kinase assay was performed in V-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme, subst...				US Patent US9598423 (2017) BindingDB Entry DOI: 10.7270/Q2FJ2JT9
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