Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cathepsin K (Homo sapiens (Human)) | BDBM150604 (US10238633, Example 278 | US8987249, 278 | US97136...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Bayer HealthCare Pharmaceuticals Corporation | Assay Description To activate the proenzyme, 5 μl procathepsin K were mixed with 1 ul activation buffer, and incubated at room temperature for 30 min.5 μL te... | J Med Chem 50: 984-1000 (2007) BindingDB Entry DOI: 10.7270/Q22R3TZF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cathepsin K (Homo sapiens (Human)) | BDBM150604 (US10238633, Example 278 | US8987249, 278 | US97136...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | 3.5 | 25 |
Boehringer Ingelheim International GmbH US Patent | Assay Description Materials: Microtiterplates (Optiplate-384 F were purchased from PerkinElmer (Prod. No. 6007270). The substrate Z-Gly-Pro-Arg-AMC was from Biomol (Pr... | US Patent US9713606 (2017) BindingDB Entry DOI: 10.7270/Q21G0P8M | |||||||||||
More data for this Ligand-Target Pair |