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Found 1 hit Enz. Inhib. hit(s) with Target = 'Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A' and Ligand = 'BDBM27376'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division cycle 7-related protein kinase [58-574]/Protein DBF4 homolog A


(Homo sapiens (Human))		BDBM27376
PNG
(2-(2-aminopyrimidin-4-yl)-7-[3-(benzyloxy)propyl]-...)
Show SMILES Nc1nccc(n1)-c1cc2c([nH]1)C(CCCOCc1ccccc1)CNC2=O
Show InChI InChI=1S/C21H23N5O2/c22-21-23-9-8-17(26-21)18-11-16-19(25-18)15(12-24-20(16)27)7-4-10-28-13-14-5-2-1-3-6-14/h1-3,5-6,8-9,11,15,25H,4,7,10,12-13H2,(H,24,27)(H2,22,23,26)
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n/an/a 24n/an/an/an/an/an/a



Nerviano Medical Sciences Srl



Assay Description
The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...

J Med Chem 52: 293-307 (2009)


Article DOI: 10.1021/jm800977q
BindingDB Entry DOI: 10.7270/Q27W69JX
More data for this
Ligand-Target Pair