BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'Cholesteryl ester transfer protein' and Ligand = 'BDBM50094519'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human CETP by scintillation proximity assay				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Concentration required for 50% inhibition of cholesteryl ester transfer protein in presence of buffer.				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
Pharmacia Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Oryctolagus cuniculus)	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Al-Zaytoonah Private University of Jordan Curated by ChEMBL					Assay Description Inhibition of CETP in rabbit serum after 1 hr by fluorescent cholesteryl esters transfer assay				Eur J Med Chem 45: 1598-617 (2010) Article DOI: 10.1016/j.ejmech.2009.12.070 BindingDB Entry DOI: 10.7270/Q2VQ32VS
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of CETP assessed as transfer of [3H]cholesterol esters from HDL to LDL				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research Curated by ChEMBL					Assay Description Inhibition of recombinant human CETP-mediated transfer of [3H]-CE from HDL to LDL				J Med Chem 43: 4575-8 (2001) BindingDB Entry DOI: 10.7270/Q2X0669S
Pharmacia Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of CETP in human whole plasma				Bioorg Med Chem Lett 18: 2640-4 (2008) Article DOI: 10.1016/j.bmcl.2008.03.030 BindingDB Entry DOI: 10.7270/Q2V40W3V
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research Curated by ChEMBL					Assay Description Tested for inhibiting CETP-mediated transfer of [3H]-CE from HDL to LDL in vitro under buffered assay conditions in human serum.				J Med Chem 43: 4575-8 (2001) BindingDB Entry DOI: 10.7270/Q2X0669S
Pharmacia Discovery Research Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Curated by ChEMBL					Assay Description Inhibition of cholesteryl ester transfer protein in presence of human serum				J Med Chem 45: 3891-904 (2002) BindingDB Entry DOI: 10.7270/Q2JW8D7P
Pharmacia Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human CETP assessed as transfer of [3H]cholesterol esters from HDL to LDL in humna plasma				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research (Pfizer Global Research and Development) Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in buffer				J Med Chem 46: 2152-68 (2003) Article DOI: 10.1021/jm020528+ BindingDB Entry DOI: 10.7270/Q2QV3KWK
					More data for this Ligand-Target Pair
Cholesteryl ester transfer protein (Homo sapiens (Human))	BDBM50094519 ((R)-1,1,1-Trifluoro-3-{(3-phenoxy-phenyl)-[3-(1,1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.40E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Discovery Research (Pfizer Global Research and Development) Curated by ChEMBL					Assay Description Compound was tested in vitro for inhibitory activity against recombinant human cholesteryl ester transfer protein in human serum				J Med Chem 46: 2152-68 (2003) Article DOI: 10.1021/jm020528+ BindingDB Entry DOI: 10.7270/Q2QV3KWK
					More data for this Ligand-Target Pair