Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Chymase' and Ligand = 'BDBM50208234'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chymase (Homo sapiens (Human))	BDBM50208234 (1-(benzo[b]thiophen-3-yl)-2-(naphthalen-2-ylamino)...) Show SMILES OP(O)(=O)C(C(=O)Nc1ccc2ccccc2c1)c1csc2ccccc12 Show InChI InChI=1S/C20H16NO4PS/c22-20(21-15-10-9-13-5-1-2-6-14(13)11-15)19(26(23,24)25)17-12-27-18-8-4-3-7-16(17)18/h1-12,19H,(H,21,22)(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of human skin chymase				J Med Chem 50: 1727-30 (2007) Article DOI: 10.1021/jm0700619 BindingDB Entry DOI: 10.7270/Q26W99RF
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