Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Coagulation factor X' and Ligand = 'BDBM17656'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM17656 (6-(5-chlorothiophen-2-yl)-N-[(3S)-1-[(2S)-1-(morph...) Show SMILES C[C@H](N1CC[C@H](NS(=O)(=O)c2ccc(nc2)-c2ccc(Cl)s2)C1=O)C(=O)N1CCOCC1 |r| Show InChI InChI=1S/C20H23ClN4O5S2/c1-13(19(26)24-8-10-30-11-9-24)25-7-6-16(20(25)27)23-32(28,29)14-2-3-15(22-12-14)17-4-5-18(21)31-17/h2-5,12-13,16,23H,6-11H2,1H3/t13-,16-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	24	-43.1	n/a	n/a	n/a	n/a	n/a	7.4	22
GSK					Assay Description The ability of test compounds to inhibit human fXa in vitro was determined in a fluorescence assay using rhodamime 110, bis-(Boc-L-glycylglycyl-L-arg...				J Med Chem 50: 1546-57 (2007) Article DOI: 10.1021/jm060870c BindingDB Entry DOI: 10.7270/Q2F18X06
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