Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Cobra venom factor/Complement factor B/Complement factor D' and Ligand = 'BDBM251439'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cobra venom factor/Complement factor B/Complement factor D (Naja kaouthia (Monocled cobra) (Naja siamensis)-Ho...)	BDBM251439 (US9452990, 121) Show SMILES COc1cc2c(N)nc(nc2c(F)c1OC)N1CCN(C[C@@H]1c1ccccc1)C(=O)C[C@@H]1CCCCN1 |r| Show InChI InChI=1S/C27H33FN6O3/c1-36-21-15-19-24(23(28)25(21)37-2)31-27(32-26(19)29)34-13-12-33(16-20(34)17-8-4-3-5-9-17)22(35)14-18-10-6-7-11-30-18/h3-5,8-9,15,18,20,30H,6-7,10-14,16H2,1-2H3,(H2,29,31,32)/t18-,20+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	25
NOVARTIS AG US Patent					Assay Description CVF-Bb complex prepared from purified cobra venom factor (1 μM), recombinant human complement factor B (expressed in drosophila cells and purifi...				US Patent US9452990 (2016) BindingDB Entry DOI: 10.7270/Q2H130Z9
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