Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Corticotropin-releasing factor receptor 1' and Ligand = 'BDBM131862'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin-releasing factor receptor 1 (Homo sapiens (Human))	BDBM131862 (US8835444, 2.3) Show SMILES Cc1ncc(Cl)cc1C(=O)N[C@H]1CC[C@H](Cn2cc3CCCCc3n2)CC1 |r,wU:14.15,wD:11.11,(-3.71,-2.69,;-5.04,-1.93,;-6.37,-2.69,;-7.71,-1.93,;-7.71,-.38,;-9.04,.38,;-6.37,.38,;-5.04,-.38,;-3.71,.38,;-3.71,1.93,;-2.37,-.38,;-1.04,.38,;.29,-.38,;1.63,.38,;1.63,1.93,;2.96,2.69,;4.29,1.93,;4.46,.39,;5.96,.07,;6.73,-1.26,;8.27,-1.26,;9.04,.07,;8.27,1.41,;6.73,1.41,;5.7,2.55,;.29,2.69,;-1.04,1.93,)| Show InChI InChI=1S/C21H27ClN4O/c1-14-19(10-17(22)11-23-14)21(27)24-18-8-6-15(7-9-18)12-26-13-16-4-2-3-5-20(16)25-26/h10-11,13,15,18H,2-9,12H2,1H3,(H,24,27)/t15-,18-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	318	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description Chinese hamster ovary (CHO) cells expressing either the human or rat recombinant CRF-1 or human CRF-2alpha (Chen et al, Proc Natl Acad Sci USA 90, 89...				US Patent US8835444 (2014) BindingDB Entry DOI: 10.7270/Q28K77ST
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